|Season 1, Episode 21|
|Air date||April 7, 2017|
|Written by|| Craig O'Neill |
|Directed by||Liz Allen Rosenbaum|
Murdoc moves forward with his plans for revenge against MacGyver by recruiting his recently released former cellmate to infiltrate Phoenix Complex as a “lab technician” and kill every agent inside, on the first season finale.
- Patricia Thornton and Nikki Carpenter were both mentioned but did not appear.
- Event involving Ciro were revealed but not entirely.
- Riley Davis killed someone for the first time.
- Mark Sheppard plays a fake Dr. Zito. In the original series, Sheppard's father W. Morgan Sheppard played a character named Dr. Zito, who appeared in two episodes.