- MacGyver's most frequent opponent, a master assassin who never fails—except when MacGyver gets involved. Murdoc is a master of disguise, as well as highly skilled and creative in the use of booby traps. He is also very fond of heavy weapons, including flamethrowers, bazookas, and dynamite. Murdoc's signature for each hit is to take photographs of his victims at the moment of their deaths. His first appearance in the series is presented as his second run-in with MacGyver (Season 2 Episode 18 - Partners). Murdoc returns for revenge for their first encounter—to the surprise of MacGyver, as Murdoc had apparently been killed while escaping on that occasion. Murdoc's revenge scheme not only fails, but results in him apparently being killed again. This became a recurring theme: each of Murdoc's subsequent appearances ends in another "death", which he incredibly survives, to return in a later episode.
- Murdoc also appears in:
- Season 3 Episode 8 - The Widowmaker
- Season 4 Episode 9 - Cleo Rocks
- Season 5 Episode 6 - Halloween Knights
- Season 6 Episode 19 - Strictly Business
- Season 7 Episode 3 - Obsessed
- Murdoc always screams "MACGYVER!" at the moment of his "death", except in the episode "Halloween Knights", where he and MacGyver act as allies.
- Murdoc is associated with the Homicide International Trust (HIT), an organization of assassins, until he is excommunicated for his repeated failures at MacGyver's hands.
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